Chapter 26: Reproduction and Development..Farabee..hard to beat textbook figures.

Lab Ex 15 is not done, but: Sea Urchin Development video/anim, echinoderm,

Biology and Society: Rise of the Supertwins
fig 1 has septuplets 
  1. Risks associated with using fertility drugs is covered below, with reproductive technologies
Unifying Concepts of Animal Reproduction
  1. Asexual: budding, fragmentation fig 2, parthenogenesis: aphid, Parthenon, rotifer (below blue o). 
  2. Saves energy, but clone.  ListKimball
  3. Hermaphrodites can be sequential (fishy) or simultaneous: fig 3, & a fish & a slug,
  4. human embyos: bipotential gonad & male & female ductwork until the sex is determined (~ week 6)
  5. External fertilization is most aquatic species: anemone, anatomy, fish, frog amplexus..
  6. Internal fertilization is terrestrial animals: insect mating, & aquatic mammals
  7. Sexual reproduction is more adaptive than asexual when environment is changing.
CHECKPOINT p 562
1. What is the most important genetic difference between asexual & sexual reproduction?
2. Describe three types of asexual reproduction
3. What is the advantage of sexual reproduction?


Human: hypothalamus > GnRH > ant. pituitary > FSH, LH > gonad: E & P, or T
  1. Female: fig 4-6: ovaries, fimbrae, oviduct, uterus, cervix, vagina, clitoris, labia
  2. Male: fig 6, testes, epididymis, vas deferens, seminal vesicles, prostate, urethra, penis

  3. Gametogenesis: egg & sperm formation
  4. Oogenesis, egg formation fig 7, all oocytes begin meiosis before birthovary
  5. at maturity: one egg/month is developed, & released @ ovulation, ovaries take turns:
  6. primary follicle > secondary (fluid space) > rising estrogen > LH surge > ovulation >
  7. corpus luteum forms, & secretes E & P, > if corpus albicans > menstruation

  8. spermatogenesis: fig. 8, at maturity few million/day: testis histology
  9. spermatogonia > spermatocyte > spermatid > sperm.
  10. Sertoli cell controls & secretes inhibin, interstitial cell (Leydig) secretes testosterone

  11. Regulation
  12. Male: hormonal control begins in brain, hypothalamus
  13. The events of the female reproductive cycle = fig. 9, wiki, Another
  14. Kimball: hormones: hypothalamus: GnRH > FSH, & LH which causes ovulation
  15. ovaries release E to develop & maintain ductwork, & E & P after ovulation to enable implantation
  16. If a pregnancy occurs > implanted blastocyst secretes HCG (in urine is pregnancy test)
  17. > ovaries continue secretion of E & P > uterus wall is maintained
  18. > embryo develops > placenta takes over secretion of E & P
CHECKPOINT p 569
1. where does the fetus develop?
2. correct sperm route?:
    epididymis, testis (seminiferous tubules), seminal vesicles?, prostate, urethra, ureter, vas deferens
3. one primary oocyte > ? secondary > ? eggs (ova)
4. what hormonal events trigger: menstruation?  ovulation?  puberty?  spermatogenesis? oogenesis?


Reproductive Health, on test only as it illustrates normal biology
  1. Contraception: rhythm method?, & oral contraceptive? > lowers FSH, so?
  2. Sexually Transmitted Diseases - not on test, would you trust him?
CHECKPOINT p 572
1. male equivalet of tubal ligation in females?


Human DevelopmentCarnegie Stagessame-wikiIU animDiscoveryCh
  1. Fertilization, fig 11-13, many sperm break down barriers around egg: cells & zona pellucida.
  2. Sperm's acrosome contains digestive enzymes, & only one nucleus enters egg.
  3. Then barriers form: blocks polyspermy.

  4. Basic Concepts of Embryonic Development = take one step at a time, NO blueprint
  5. zygote > cleavage > morula > blastocyst  > gastrula, fig 14, 16 & 17
  6. resource: mammals cleave like a fish, but gastrulate like a reptile & bird =
  7. along a line in the ectoderm: the primitive streak
  8. reptiles developed this way to deal with heavy yolk - impossible to cleave right through
  9. Gastrulation resource,
  10. Gastrulation produces: ectoderm, mesoderm, & endoderm: all produce epithelia, but
  11. only ectoderm produces nerve, & mesoderm produces connective tissues & muscle
  12. All any cell knows is what to do next = induction
  13. Induction occurs throughout development, produces all complex structures:
    = adjacent cells talk to each other & cooperate to produce form
  14. NOT the same meaning as inducing childbirth
  15. apoptosis, fig 15, is part of morphogenesis
  16. yellow notocord (mesoderm) induces green neural tube (ectoderm): fig is chick embryo
  17. fig 19a, eye = induction between pre-retina & pre-lens (ectoderm induces ectoderm!)
  18. every structure in the embryo is the product of induction

  19. the embryo at first digests the endometrium to grow fig 16, implantation
  20. the trophoblast fig 17, (pre-placenta) secretes human chorionic gonadotropin
  21. = pregnancy test > to keep ovary producing estrogen & progesterone to maintain endometrium

  22. in reptiles, birds & mammals, fig 18 bold, there are 4 extraembryonic membranes, human,
  23. 1) amnion: fluid bag protects embryo, amniocentesis
  24. 2) yolk sac: stores food in eggs, in mammals forms first germ cells, & blood cells
  25. 3) allantois: stores wastes in shelled eggs, in mammals forms part of umbilical cord
  26. 4) chorion: lines egg shell, in mammals forms part of the placenta & secretes hormones.
  27. Placenta becomes main source of estrogen & progesterone (scroll to figure).

  28. Development by trimester = to weeks 13, 26, 39. also too detailed,
  29. First trimester: fig 19: embryo first 8 wks: forms organs, limb buds, tail, early on vertebrates
    Second & Third trimesters
    Next 7 months fetus grows, fig 19, becomes more like infant

  30. estrogen induces oxytocin receptors on muscle cells of myometrium, fig 21
  31. & stress on mother > rising CRH > ACTH > cortisol > rising oxytocin & receptors
  32. fig 21: oxytocin, prostglandins, & decreased progesterone cause contractions in parturition
  33. The three stages of labor: dilation, expulsion, placental delivery, fig 22. Induction

  34. relaxin helps to soften ligaments & joints
  35. Nursing
  36. oxytocin also causes milk let down in . 
  37. milk synthesis/secretion = prolactin's role
CHECKPOINT p 578
In fertilization two haploid ? fuse to form a diploid ?
Put in order: organ formation, fertilization, gastrulation, cleavage
Would you expect the cells of the blastocyst to get more or less oxygen than the zygote?  Why?
Why should a woman trying to conceive try to avoid drugs, alcohol, & nicotine
Why is it important for the embryo that high levels of E & P are maintained in the mother's blood?
Why isn't a newborn immediately susceptible to numerous infections?

  1. Reproductive Technologies (not on test unless follows from normal biology)
  2. Causes of infertility, & treatments fit the cause.
  3. In vitro ( = in glass) fertilization, follows producing several eggs, induced by FSH injections
  4. Problems created by reproductive technologies: multiple births, what else?
CHECKPOINT p 580
1. Name of procedure to make test-tube baby?

2. Distinguish between infertility & impotency
3. How can five people be involved in creating one baby? chimera, image

Evolution Connection: Menopause and the Grandmother Hypothesis
  1. Fitness: female menopause is to help with raising grandchildren!
  2. Child Development & Parenting