|
| (Photo Courtesy Dr. Wesley Warren) |
Chickens
and humans... on the surface, there do not appear to be many
similarities. But at a news conference Wednesday, researchers
said they believe that recent advances in the field of chicken genetics
will help scientists solve human health problems.
If
you were to go back through your family tree some 300 million years,
you would see that you and and the chickens you may roast for dinner
share a common ancestor.
It is this evolutionary link that has scientists excited about their
increasing ability to understand a chicken's one billion DNA pairs,
which is enabling scientists to learn from the genetic similarities
between chickens and humans.
Researcher Chris Ponting, an expert in genome analysis at Oxford
University in Britain, explains that the genetic overlap between
chickens and humans represents the small fraction a human's genetic
make-up, or genome, that has been preserved for hundreds of millions of
years.
Mr. Ponting says 60 percent of human genes and chicken genes still
bears some similarity, but the 2.5 percent of the human genome that
still exactly matches the chicken genome must have been extremely
important to human survival over the centuries.
"Among these is where we can now all look first when searching for
DNA mutations linked to human disease," he explained.
Research on the chicken genome, such as the work published in the
most recent issue of the journal Nature, also helps scientists better
understand chicken development for agricultural purposes. Such
gains could help farmers produce chickens that lay more eggs or provide
more meat and less fat.
And genetic researcher Jerry Dodgson of Michigan State University
says that part of the research also has implications for human beings.
"As genes are identified that contribute to fat deposition in
broilers [chickens for roasting], we might look at the analogous human
genes for influences on obesity," he noted.
He says similar research can be conducted on reproductive processes and disease resistance.
Recent outbreaks of bird flu have increased scientists' desire to
learn about the chicken genome. Bird flu is believed to have
passed from birds to humans and killed more than 30 people in Vietnam
and Thailand this year.
Mr. Dodgson says studying various diseases in chickens might help
researchers better understand related diseases in people.
"The genome sequence is expected to help us discover genes that
enhance natural resistance to infection in birds and to better
understand and develop new vaccine strategies," he added.
Mr.
Dodgson notes that such advances require years of additional research,
but he adds that understanding the chicken genome makes that such
research possible.